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Two Tau binding sites on tubulin revealed by thiol-disulfide exchanges

Tau is a Microtubule-associated protein that induces and stabilizes the formation of the Microtubule cytoskeleton and plays an important role in neurodegenerative diseases. The Microtubules binding region of Tau has been determined for a long time but where and how Tau binds to its partner still rem...

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Detalles Bibliográficos
Autores principales: Martinho, Marlène, Allegro, Diane, Huvent, Isabelle, Chabaud, Charlotte, Etienne, Emilien, Kovacic, Hervé, Guigliarelli, Bruno, Peyrot, Vincent, Landrieu, Isabelle, Belle, Valérie, Barbier, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138654/
https://www.ncbi.nlm.nih.gov/pubmed/30218010
http://dx.doi.org/10.1038/s41598-018-32096-9