Integrative analysis of differentially expressed genes and miRNAs predicts complex T3-mediated protective circuits in a rat model of cardiac ischemia reperfusion

Thyroid hormone (T3) dyshomeostasis in the cardiac ischemia-reperfusion (IR) setting negatively impacts on mitochondria function and extracellular matrix remodeling. The modulation of cardiac miRNAs may represent the underlying molecular mechanisms, but a systems biology perspective investigating th...

Descripción completa

Detalles Bibliográficos
Autores principales: Forini, Francesca, Nicolini, Giuseppina, Kusmic, Claudia, D’Aurizio, Romina, Rizzo, Milena, Baumgart, Mario, Groth, Marco, Doccini, Stefano, Iervasi, Giorgio, Pitto, Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138681/
https://www.ncbi.nlm.nih.gov/pubmed/30218079
http://dx.doi.org/10.1038/s41598-018-32237-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138681/
https://www.ncbi.nlm.nih.gov/pubmed/30218079
http://dx.doi.org/10.1038/s41598-018-32237-0

Ejemplares similares