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Deregulation of Notch1 pathway and circulating endothelial progenitor cell (EPC) number in patients with bicuspid aortic valve with and without ascending aorta aneurysm

Bicuspid aortic valve (BAV) is frequently associated with the development of ascending aortic aneurysm, even if the underlying mechanisms remain to be clarified. Here, we investigated if a deregulation of Notch1 signaling pathway and endothelial progenitor cells (EPCs) number is associated with BAV...

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Detalles Bibliográficos
Autores principales: Balistreri, Carmela R., Crapanzano, Floriana, Schirone, Leonardo, Allegra, Alberto, Pisano, Calogera, Ruvolo, Giovanni, Forte, Maurizio, Greco, Ernesto, Cavarretta, Elena, Marullo, Antonino G. M., Sciarretta, Sebastiano, Frati, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138685/
https://www.ncbi.nlm.nih.gov/pubmed/30218064
http://dx.doi.org/10.1038/s41598-018-32170-2