Imaging of human cells exposed to an antifungal antibiotic amphotericin B reveals the mechanisms associated with the drug toxicity and cell defence

Amphotericin B is an antibiotic used in pharmacotherapy of life-threatening mycotic infections. Unfortunately, the applicability of this antibiotic is associated with highly toxic side effects. In order to understand molecular mechanisms underlying toxicity of amphotericin B to patients, two cell li...

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Detalles Bibliográficos
Autores principales: Grela, Ewa, Piet, Mateusz, Luchowski, Rafal, Grudzinski, Wojciech, Paduch, Roman, Gruszecki, Wieslaw I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138690/
https://www.ncbi.nlm.nih.gov/pubmed/30218099
http://dx.doi.org/10.1038/s41598-018-32301-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138690/
https://www.ncbi.nlm.nih.gov/pubmed/30218099
http://dx.doi.org/10.1038/s41598-018-32301-9

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