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Long-range haplotype analysis of the malaria parasite receptor gene ACKR1 in an East-African population

The human ACKR1 gene encodes a glycoprotein expressing the Duffy blood group antigens (Fy). The Duffy protein acts as a receptor for distinct pro-inflammatory cytokines and malaria parasites. We determined the haplotypes of the ACKR1 gene in a population inhabiting a malaria-endemic area. We collect...

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Detalles Bibliográficos
Autores principales: Yin, Qinan, Srivastava, Kshitij, Gebremedhin, Amha, Makuria, Addisalem Taye, Flegel, Willy Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138691/
https://www.ncbi.nlm.nih.gov/pubmed/30245840
http://dx.doi.org/10.1038/s41439-018-0024-8