Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5

The GTPase Rab11 plays key roles in receptor recycling, oogenesis, autophagosome formation, and ciliogenesis. However, investigating Rab11 regulation has been hindered by limited molecular detail describing activation by cognate guanine nucleotide exchange factors (GEFs). Here, we present the struct...

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Detalles Bibliográficos
Autores principales: Jenkins, Meredith L., Margaria, Jean Piero, Stariha, Jordan T. B., Hoffmann, Reece M., McPhail, Jacob A., Hamelin, David J., Boulanger, Martin J., Hirsch, Emilio, Burke, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138693/
https://www.ncbi.nlm.nih.gov/pubmed/30217979
http://dx.doi.org/10.1038/s41467-018-06196-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138693/
https://www.ncbi.nlm.nih.gov/pubmed/30217979
http://dx.doi.org/10.1038/s41467-018-06196-z

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