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Susceptibility to Plasmodium vivax malaria associated with DARC (Duffy antigen) polymorphisms is influenced by the time of exposure to malaria

Malaria has provided a major selective pressure and has modulated the genetic diversity of the human genome. The variants of the Duffy Antigen/Receptor for Chemokines (DARC) gene have probably been selected by malaria parasites, particularly the FY*O allele, which is fixed in sub-Saharan Africa and...

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Detalles Bibliográficos
Autores principales: Kano, Flora Satiko, de Souza, Aracele Maria, de Menezes Torres, Leticia, Costa, Marcelo Azevedo, Souza-Silva, Flávia Alessandra, Sanchez, Bruno Antônio Marinho, Fontes, Cor Jesus Fernandes, Soares, Irene Silva, de Brito, Cristiana Ferreira Alves, Carvalho, Luzia Helena, Sousa, Tais Nobrega
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138695/
https://www.ncbi.nlm.nih.gov/pubmed/30218021
http://dx.doi.org/10.1038/s41598-018-32254-z