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The m(6)A-methylase complex recruits TREX and regulates mRNA export

N(6)-methyladenosine (m(6)A) is the most abundant internal modification of eukaryotic mRNA. This modification has previously been shown to alter the export kinetics for mRNAs though the molecular details surrounding this phenomenon remain poorly understood. Recruitment of the TREX mRNA export comple...

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Detalles Bibliográficos
Autores principales: Lesbirel, Simon, Viphakone, Nicolas, Parker, Matthew, Parker, Jacob, Heath, Catherine, Sudbery, Ian, Wilson, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138711/
https://www.ncbi.nlm.nih.gov/pubmed/30218090
http://dx.doi.org/10.1038/s41598-018-32310-8