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Ketamine reduces aversion in rodent pain models by suppressing hyperactivity of the anterior cingulate cortex

Chronic pain is known to induce an amplified aversive reaction to peripheral nociceptive inputs. This enhanced affective response constitutes a key pathologic feature of chronic pain syndromes such as fibromyalgia. However, the neural mechanisms that underlie this important aspect of pain processing...

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Detalles Bibliográficos
Autores principales: Zhou, Haocheng, Zhang, Qiaosheng, Martinez, Erik, Dale, Jahrane, Hu, Sile, Zhang, Eric, Liu, Kevin, Huang, Dong, Yang, Guang, Chen, Zhe, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138720/
https://www.ncbi.nlm.nih.gov/pubmed/30218052
http://dx.doi.org/10.1038/s41467-018-06295-x