Kartogenin inhibits pain behavior, chondrocyte inflammation, and attenuates osteoarthritis progression in mice through induction of IL-10

Osteoarthritis (OA) is a major degenerative joint condition that causes articular cartilage destruction. It was recently found that enhancement of chondroclasts and suppression in Treg cell differentiation are involved in the pathogenesis of OA. Kartogenin (KGN) is a small drug-like molecule that in...

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Detalles Bibliográficos
Autores principales: Kwon, Ji Ye, Lee, Seung Hoon, Na, Hyun-Sik, Jung, KyungAh, Choi, JeongWon, Cho, Keun Hyung, Lee, Chang-Yong, Kim, Seok Jung, Park, Sung-Hwan, Shin, Dong-Yun, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138726/
https://www.ncbi.nlm.nih.gov/pubmed/30218055
http://dx.doi.org/10.1038/s41598-018-32206-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138726/
https://www.ncbi.nlm.nih.gov/pubmed/30218055
http://dx.doi.org/10.1038/s41598-018-32206-7

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