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Computational prediction of vaccine potential epitopes and 3-dimensional structure of XAGE-1b for non-small cell lung cancer immunotherapy

BACKGROUND: XAGE-1b is shown to be overexpressed in lung adenocarcinoma and to be a strong immunogenic antigen among non-small cell lung cancer (NSCLC) patients. However, 3D structure of XAGE-1b is not available and its confirmation has not been solved yet. METHODS: Multiple sequence alignment was r...

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Detalles Bibliográficos
Autores principales: Tarek, Mohammad M., Shafei, Ayman E., Ali, Mahmoud A., Mansour, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138771/
https://www.ncbi.nlm.nih.gov/pubmed/29866600
http://dx.doi.org/10.1016/j.bj.2018.04.002