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Purinergic signalling in autoimmunity: A role for the P2X7R in systemic lupus erythematosus?

Purinergic signalling plays a crucial role in immunity and autoimmunity. Among purinergic receptors, the P2X7 receptor (P2X7R) has an undisputed role as it is expressed to high level by immune cells, triggers cytokine release and modulates immune cell differentiation. In this review, we focus on evi...

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Detalles Bibliográficos
Autores principales: Di Virgilio, Francesco, Giuliani, Anna Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138817/
https://www.ncbi.nlm.nih.gov/pubmed/27884379
http://dx.doi.org/10.1016/j.bj.2016.08.006