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Genomic analysis of transcriptional networks directing progression of cell states during MGE development

BACKGROUND: Homeodomain (HD) transcription factor (TF) NKX2–1 critical for the regional specification of the medial ganglionic eminence (MGE) as well as promoting the GABAergic and cholinergic neuron fates via the induction of TFs such as LHX6 and LHX8. NKX2–1 defines MGE regional identity in large...

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Detalles Bibliográficos
Autores principales: Sandberg, Magnus, Taher, Leila, Hu, Jianxin, Black, Brian L., Nord, Alex S., Rubenstein, John L. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138899/
https://www.ncbi.nlm.nih.gov/pubmed/30217225
http://dx.doi.org/10.1186/s13064-018-0119-4