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Genomic analysis of transcriptional networks directing progression of cell states during MGE development
BACKGROUND: Homeodomain (HD) transcription factor (TF) NKX2–1 critical for the regional specification of the medial ganglionic eminence (MGE) as well as promoting the GABAergic and cholinergic neuron fates via the induction of TFs such as LHX6 and LHX8. NKX2–1 defines MGE regional identity in large...
Autores principales: | Sandberg, Magnus, Taher, Leila, Hu, Jianxin, Black, Brian L., Nord, Alex S., Rubenstein, John L. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138899/ https://www.ncbi.nlm.nih.gov/pubmed/30217225 http://dx.doi.org/10.1186/s13064-018-0119-4 |
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