Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Repetitive injury and reprogramming of the lung epithelium are thought to be critical drivers of disease progression, contributing to fibroblast activation, extracellular matrix remodeling, and subsequently loss of...

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Detalles Bibliográficos
Autores principales: Lehmann, Mareike, Buhl, Lara, Alsafadi, Hani N., Klee, Stephan, Hermann, Sarah, Mutze, Kathrin, Ota, Chiharu, Lindner, Michael, Behr, Jürgen, Hilgendorff, Anne, Wagner, Darcy E., Königshoff, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138909/
https://www.ncbi.nlm.nih.gov/pubmed/30219058
http://dx.doi.org/10.1186/s12931-018-0876-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138909/
https://www.ncbi.nlm.nih.gov/pubmed/30219058
http://dx.doi.org/10.1186/s12931-018-0876-y

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