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Up-regulated expression of E2F2 is necessary for p16INK4a-induced cartilage injury
BACKGROUND: Cartilage degradation would result in osteoarthritis (OA). p16INK4awas found in some age-related diseases. In this study, we aimed to determine the role of p16INK4a during OA and to investigate the underlying mechanisms. METHODS: Enzyme-linked immunosorbent assay (ELISA) was performed to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138916/ https://www.ncbi.nlm.nih.gov/pubmed/30219053 http://dx.doi.org/10.1186/s12891-018-2253-x |