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Exome sequencing study in patients with multiple sclerosis reveals variants associated with disease course

BACKGROUND: It remains unclear whether disease course in multiple sclerosis (MS) is influenced by genetic polymorphisms. Here, we aimed to identify genetic variants associated with benign and aggressive disease courses in MS patients. METHODS: MS patients were classified into benign and aggressive p...

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Detalles Bibliográficos
Autores principales: Gil-Varea, Elia, Urcelay, Elena, Vilariño-Güell, Carles, Costa, Carme, Midaglia, Luciana, Matesanz, Fuencisla, Rodríguez-Antigüedad, Alfredo, Oksenberg, Jorge, Espino-Paisan, Laura, Dessa Sadovnick, A., Saiz, Albert, Villar, Luisa M., García-Merino, Juan Antonio, Ramió-Torrentà, Lluís, Triviño, Juan Carlos, Quintana, Ester, Robles, René, Sánchez-López, Antonio, Arroyo, Rafael, Alvarez-Cermeño, Jose C., Vidal-Jordana, Angela, Malhotra, Sunny, Fissolo, Nicolas, Montalban, Xavier, Comabella, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138928/
https://www.ncbi.nlm.nih.gov/pubmed/30217166
http://dx.doi.org/10.1186/s12974-018-1307-1