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Phage spanins: diversity, topological dynamics and gene convergence

BACKGROUND: Spanins are phage lysis proteins required to disrupt the outer membrane. Phages employ either two-component spanins or unimolecular spanins in this final step of Gram-negative host lysis. Two-component spanins like Rz-Rz1 from phage lambda consist of an integral inner membrane protein: i...

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Detalles Bibliográficos
Autores principales: Kongari, Rohit, Rajaure, Manoj, Cahill, Jesse, Rasche, Eric, Mijalis, Eleni, Berry, Joel, Young, Ry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139136/
https://www.ncbi.nlm.nih.gov/pubmed/30219026
http://dx.doi.org/10.1186/s12859-018-2342-8