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Accurate flexible refinement of atomic models against medium-resolution cryo-EM maps using damped dynamics

BACKGROUND: Dramatic progress has recently been made in cryo-electron microscopy technologies, which now make possible the reconstruction of a growing number of biomolecular structures to near-atomic resolution. However, the need persists for fitting and refinement approaches that address those case...

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Detalles Bibliográficos
Autores principales: Kovacs, Julio A., Galkin, Vitold E., Wriggers, Willy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139150/
https://www.ncbi.nlm.nih.gov/pubmed/30219048
http://dx.doi.org/10.1186/s12900-018-0089-0