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LMO3 promotes hepatocellular carcinoma invasion, metastasis and anoikis inhibition by directly interacting with LATS1 and suppressing Hippo signaling

BACKGROUND: In this research, we aimed to investigate the biological functions of LIM domain only 3 (LMO3) in hepatocellular carcinoma (HCC) and uncover the underlying molecular mechanism in it. METHODS: HCC tissue microarray (n = 180) was used to analyze the correlation between LMO3 expression and...

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Detalles Bibliográficos
Autores principales: Cheng, Yang, Hou, Tianlu, Ping, Jian, Chen, Tianyang, Yin, Baobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139164/
https://www.ncbi.nlm.nih.gov/pubmed/30219064
http://dx.doi.org/10.1186/s13046-018-0903-3