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Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2

BACKGROUND: Mast cells may activate fibroblasts and contribute to remodeling processes in the lung. However, the mechanism behind these actions needs to be further investigated. Fibroblasts are major regulators of on-going remodeling processes. Protease activated receptor 2 (PAR2) expressed by fibro...

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Detalles Bibliográficos
Autores principales: Bagher, Mariam, Larsson-Callerfelt, Anna-Karin, Rosmark, Oskar, Hallgren, Oskar, Bjermer, Leif, Westergren-Thorsson, Gunilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139170/
https://www.ncbi.nlm.nih.gov/pubmed/30219079
http://dx.doi.org/10.1186/s12964-018-0269-3