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The Pattern of mRNA Expression Is Changed in Sinoatrial Node from Goto-Kakizaki Type 2 Diabetic Rat Heart

BACKGROUND: In vivo experiments in Goto-Kakizaki (GK) type 2 diabetic rats have demonstrated reductions in heart rate from a young age. The expression of genes encoding more than 70 proteins that are associated with the generation and conduction of electrical activity in the GK sinoatrial node (SAN)...

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Detalles Bibliográficos
Autores principales: Howarth, F. C., Qureshi, M. A., Jayaprakash, P., Parekh, K., Oz, M., Dobrzynski, H., Adrian, T. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139199/
https://www.ncbi.nlm.nih.gov/pubmed/30246030
http://dx.doi.org/10.1155/2018/8454078