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Comparative Glycopeptide Analysis for Protein Glycosylation by Liquid Chromatography and Tandem Mass Spectrometry: Variation in Glycosylation Patterns of Site-Directed Mutagenized Glycoprotein

Glycosylation is one of the most important posttranslational modifications for proteins, including therapeutic antibodies, and greatly influences protein physiochemical properties. In this study, glycopeptide mapping of a reference and biosimilar recombinant antibodies (rAbs) was performed using liq...

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Detalles Bibliográficos
Autores principales: Hahm, Young Hye, Hahm, Sung Ho, Jo, Hyoun Young, Ahn, Yeong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139207/
https://www.ncbi.nlm.nih.gov/pubmed/30245723
http://dx.doi.org/10.1155/2018/8605021