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Dominant Negative FADD/MORT1 Inhibits the Development of Intestinal Intraepithelial Lymphocytes With a Marked Defect on CD8αα+TCRγδ+ T Cells

Intestinal intraepithelial lymphocytes (IELs) play a critical role in mucosal immune system, which differ from thymus-derived cells and develop locally in gut. Although the development of IELs has been studied in some detail, the molecular cues controlling their local development remain unclear. Her...

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Detalles Bibliográficos
Autores principales: Zhang, Xuerui, Huo, Lina, Song, Lulu, Hu, Zhaoqing, Wang, Xinran, Han, Yuheng, Wang, Ying, Xu, Peipei, Zhang, Jing, Hua, Zi-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139313/
https://www.ncbi.nlm.nih.gov/pubmed/30250469
http://dx.doi.org/10.3389/fimmu.2018.02038