Nutrient-Driven O-GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution

Nutrient-driven O-GlcNAcylation has been linked to epigenetic regulation of gene expression in metazoans. In C. elegans, O-GlcNAc marks the promoters of over 800 developmental, metabolic, and stress-related genes; these O-GlcNAc marked genes show a strong 5′, promoter-proximal bias in the distributi...

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Detalles Bibliográficos
Autores principales: Krause, Michael W., Love, Dona C., Ghosh, Salil K., Wang, Peng, Yun, Sijung, Fukushige, Tetsunari, Hanover, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139338/
https://www.ncbi.nlm.nih.gov/pubmed/30250452
http://dx.doi.org/10.3389/fendo.2018.00521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139338/
https://www.ncbi.nlm.nih.gov/pubmed/30250452
http://dx.doi.org/10.3389/fendo.2018.00521

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