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Stochastically Timed Competition Between Division and Differentiation Fates Regulates the Transition From B Lymphoblast to Plasma Cell

In response to external stimuli, naïve B cells proliferate and take on a range of fates important for immunity. How their fate is determined is a topic of much recent research, with candidates including asymmetric cell division, lineage priming, stochastic assignment, and microenvironment instructio...

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Detalles Bibliográficos
Autores principales: Zhou, Jie H. S., Markham, John F., Duffy, Ken R., Hodgkin, Philip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139340/
https://www.ncbi.nlm.nih.gov/pubmed/30250473
http://dx.doi.org/10.3389/fimmu.2018.02053