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Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications

As people age, iron deposits in different areas of the brain may impair normal cognitive function and behavior. Abnormal iron metabolism generates hydroxyl radicals through the Fenton reaction, triggers oxidative stress reactions, damages cell lipids, protein and DNA structure and function, and ulti...

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Detalles Bibliográficos
Autores principales: Liu, Jun-Lin, Fan, Yong-Gang, Yang, Zheng-Sheng, Wang, Zhan-You, Guo, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139360/
https://www.ncbi.nlm.nih.gov/pubmed/30250423
http://dx.doi.org/10.3389/fnins.2018.00632