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A sulfur-free peptide mimic of surfactant protein B (B-YL) exhibits high in vitro and in vivo surface activities

Background: Animal-derived surfactants containing surfactant proteins B (SP-B) and C (SP-C) are used to treat respiratory distress syndrome (RDS) in preterm infants. SP-B (79 residues) plays a pivotal role in lung function and the design of synthetic lung surfactant. Super Mini-B (SMB), a 41-residue...

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Detalles Bibliográficos
Autores principales: Walther, Frans J., Gupta, Monik, Gordon, Larry M., Waring, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139377/
https://www.ncbi.nlm.nih.gov/pubmed/30234192
http://dx.doi.org/10.12688/gatesopenres.12799.2