Cue-Polarized Transport of β-actin mRNA Depends on 3′UTR and Microtubules in Live Growth Cones

Guidance cues trigger fast responses in axonal growth cones such as directional turning and collapse that require local protein synthesis. An attractive cue-gradient, such as Netrin-1, triggers de novo synthesis of β-actin localized to the near-side compartment of the growth cone that promotes F-act...

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Detalles Bibliográficos
Autores principales: Leung, Kin-Mei, Lu, Bo, Wong, Hovy Ho-Wai, Lin, Julie Qiaojin, Turner-Bridger, Benita, Holt, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139529/
https://www.ncbi.nlm.nih.gov/pubmed/30250426
http://dx.doi.org/10.3389/fncel.2018.00300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139529/
https://www.ncbi.nlm.nih.gov/pubmed/30250426
http://dx.doi.org/10.3389/fncel.2018.00300

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