Structural and functional effects of myosin-binding protein-C phosphorylation in heart muscle are not mimicked by serine-to-aspartate substitutions

Myosin-binding protein-C (cMyBP-C) is a key regulator of contractility in heart muscle, and its regulatory function is controlled in turn by phosphorylation of multiple serines in its m-domain. The structural and functional effects of m-domain phosphorylation have often been inferred from those of t...

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Detalles Bibliográficos
Autores principales: Kampourakis, Thomas, Ponnam, Saraswathi, Sun, Yin-Biao, Sevrieva, Ivanka, Irving, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Accelerated Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139572/
https://www.ncbi.nlm.nih.gov/pubmed/30082313
http://dx.doi.org/10.1074/jbc.AC118.004816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139572/
https://www.ncbi.nlm.nih.gov/pubmed/30082313
http://dx.doi.org/10.1074/jbc.AC118.004816

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