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The vagal ganglia transcriptome identifies candidate therapeutics for airway hyperreactivity

Mainstay therapeutics are ineffective in some people with asthma, suggesting a need for additional agents. In the current study, we used vagal ganglia transcriptome profiling and connectivity mapping to identify compounds beneficial for alleviating airway hyperreactivity (AHR). As a comparison, we a...

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Detalles Bibliográficos
Autores principales: Reznikov, Leah R., Meyerholz, David K., Abou Alaiwa, Mahmoud, Kuan, Shin-Ping, Liao, Yan-Shin J., Bormann, Nicholas L., Bair, Thomas B., Price, Margaret, Stoltz, David A., Welsh, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139658/
https://www.ncbi.nlm.nih.gov/pubmed/29631359
http://dx.doi.org/10.1152/ajplung.00557.2017