Molecular Phenotyping of Telomerized Human Bone Marrow Skeletal Stem Cells Reveals a Genetic Program of Enhanced Proliferation and Maintenance of Differentiation Responses

Long‐term in vitro expansion of bone marrow stromal (skeletal) stem cells (also known as human mesenchymal stem cells [hMSC]) is associated with replicative senescence and impaired functions. We have previously reported that telomerization of hMSC through hTERT overexpression led to bypassing a repl...

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Detalles Bibliográficos
Autores principales: Twine, Natalie A, Harkness, Linda, Adjaye, James, Aldahmash, Abdullah, Wilkins, Marc R, Kassem, Moustapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139702/
https://www.ncbi.nlm.nih.gov/pubmed/30283907
http://dx.doi.org/10.1002/jbm4.10050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139702/
https://www.ncbi.nlm.nih.gov/pubmed/30283907
http://dx.doi.org/10.1002/jbm4.10050

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