Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels

As part of an ongoing program to develop potential therapeutic agents for the treatment of the neurodegenerative disease Friedreich׳s ataxia (FRDA), we have prepared a number of lipophilic methylene blue analogues. Some of these compounds significantly increase mitochondrial biogenesis and frataxin...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Indrajit, Chowdhury, Sandipan Roy, Visavadiya, Nishant P., Hecht, Sidney M., Khdour, Omar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139889/
https://www.ncbi.nlm.nih.gov/pubmed/30225325
http://dx.doi.org/10.1016/j.dib.2018.08.156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139889/
https://www.ncbi.nlm.nih.gov/pubmed/30225325
http://dx.doi.org/10.1016/j.dib.2018.08.156

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