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Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels
As part of an ongoing program to develop potential therapeutic agents for the treatment of the neurodegenerative disease Friedreich׳s ataxia (FRDA), we have prepared a number of lipophilic methylene blue analogues. Some of these compounds significantly increase mitochondrial biogenesis and frataxin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139889/ https://www.ncbi.nlm.nih.gov/pubmed/30225325 http://dx.doi.org/10.1016/j.dib.2018.08.156 |