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Dexmedetomidine Ameliorates Acute Stress-Induced Kidney Injury by Attenuating Oxidative Stress and Apoptosis through Inhibition of the ROS/JNK Signaling Pathway

Acute stress induces tissue damage through excessive oxidative stress. Dexmedetomidine (DEX) reportedly has an antioxidant effect. However, protective roles and related potential molecular mechanisms of DEX against kidney injury induced by acute stress are unknown. Herein, rats were forced to swim 1...

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Detalles Bibliográficos
Autores principales: Chen, Yongping, Feng, Xiujing, Hu, Xueyuan, Sha, Jichen, Li, Bei, Zhang, Huayun, Fan, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140004/
https://www.ncbi.nlm.nih.gov/pubmed/30250633
http://dx.doi.org/10.1155/2018/4035310