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Differential Involvement of Kinase Activity of Ca(2+)/Calmodulin-Dependent Protein Kinase IIα in Hippocampus- and Amygdala-Dependent Memory Revealed by Kinase-Dead Knock-In Mouse
Ca(2+)/calmodulin-dependent protein kinase IIα (CaMKIIα) is a key mediator of activity-dependent neuronal modifications and has been implicated in the molecular mechanisms of learning and memory. Indeed, several types of CaMKIIα knock-in (KI) and knock-out (KO) mice revealed impairments in hippocamp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140109/ https://www.ncbi.nlm.nih.gov/pubmed/30225347 http://dx.doi.org/10.1523/ENEURO.0133-18.2018 |