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Differential Involvement of Kinase Activity of Ca(2+)/Calmodulin-Dependent Protein Kinase IIα in Hippocampus- and Amygdala-Dependent Memory Revealed by Kinase-Dead Knock-In Mouse

Ca(2+)/calmodulin-dependent protein kinase IIα (CaMKIIα) is a key mediator of activity-dependent neuronal modifications and has been implicated in the molecular mechanisms of learning and memory. Indeed, several types of CaMKIIα knock-in (KI) and knock-out (KO) mice revealed impairments in hippocamp...

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Detalles Bibliográficos
Autores principales: Yamagata, Yoko, Yanagawa, Yuchio, Imoto, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140109/
https://www.ncbi.nlm.nih.gov/pubmed/30225347
http://dx.doi.org/10.1523/ENEURO.0133-18.2018