Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology

Phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) reflects neurite degeneration at the early stage of Alzheimer’s disease (AD), before extracellular Aβ aggregates are histologically detectable. Here, we demonstrate that similar changes in MARCKS occur in Parkinson’s disease (...

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Detalles Bibliográficos
Autores principales: Fujita, Kyota, Homma, Hidenori, Kondo, Kanoh, Ikuno, Masashi, Yamakado, Hodaka, Tagawa, Kazuhiko, Murayama, Shigeo, Takahashi, Ryosuke, Okazawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116/
https://www.ncbi.nlm.nih.gov/pubmed/30225354
http://dx.doi.org/10.1523/ENEURO.0217-18.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116/
https://www.ncbi.nlm.nih.gov/pubmed/30225354
http://dx.doi.org/10.1523/ENEURO.0217-18.2018

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