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Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology
Phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) reflects neurite degeneration at the early stage of Alzheimer’s disease (AD), before extracellular Aβ aggregates are histologically detectable. Here, we demonstrate that similar changes in MARCKS occur in Parkinson’s disease (...
Autores principales: | Fujita, Kyota, Homma, Hidenori, Kondo, Kanoh, Ikuno, Masashi, Yamakado, Hodaka, Tagawa, Kazuhiko, Murayama, Shigeo, Takahashi, Ryosuke, Okazawa, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140116/ https://www.ncbi.nlm.nih.gov/pubmed/30225354 http://dx.doi.org/10.1523/ENEURO.0217-18.2018 |
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