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Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin

The endo-lysosomal network serves an essential role in determining the fate of endocytosed transmembrane proteins and their associated proteins and lipids. Sorting nexins (SNXs) play a central role in the functional organisation of this network. Comprising over 30 proteins in humans, SNXs are classi...

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Detalles Bibliográficos
Autores principales: Danson, Chris M., Pearson, Neil, Heesom, Kate J., Cullen, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140323/
https://www.ncbi.nlm.nih.gov/pubmed/30072438
http://dx.doi.org/10.1242/jcs.211672