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Inhibition of JAK2/STAT3 Signaling Pathway Suppresses Proliferation of Burkitt’s Lymphoma Raji Cells via Cell Cycle Progression, Apoptosis, and Oxidative Stress by Modulating HSP70

BACKGROUND: The aim of this study was to investigate the effect of the JAK2/STAT3 pathway on the proliferation, cell cycle distribution, apoptosis, and oxidative stress of Raji cells via regulating HSP70 expression. MATERIAL/METHODS: Raji cells were divided into Blank, HSP70 siRNA, NC siRNA, AG490 (...

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Detalles Bibliográficos
Autores principales: Xu, Neng-Wen, Chen, Yu, Liu, Wei’e, Chen, Yan-Jie, Fan, Zhi-Min, Liu, Min, Li, Lin-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140376/
https://www.ncbi.nlm.nih.gov/pubmed/30194286
http://dx.doi.org/10.12659/MSM.910170