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Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD

Extracellular small RNAs (sRNAs), including microRNAs (miRNAs), are promising biomarkers for diseases such as Duchenne muscular dystrophy (DMD), although their biological relevance is largely unknown. To investigate the relationship between intracellular and extracellular sRNA levels on a global sca...

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Detalles Bibliográficos
Autores principales: Coenen-Stass, Anna M.L., Sork, Helena, Gatto, Sole, Godfrey, Caroline, Bhomra, Amarjit, Krjutškov, Kaarel, Hart, Jonathan R., Westholm, Jakub O., O’Donovan, Liz, Roos, Andreas, Lochmüller, Hanns, Puri, Pier Lorenzo, EL Andaloussi, Samir, Wood, Matthew J.A., Roberts, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140421/
https://www.ncbi.nlm.nih.gov/pubmed/30219269
http://dx.doi.org/10.1016/j.omtn.2018.08.005