Nano LC-MS using capillary columns enables accurate quantification of modified ribonucleosides at low femtomol levels

Post-transcriptional chemical modifications of (t)RNA molecules are crucial in fundamental biological processes, such as translation. Despite their biological importance and accumulating evidence linking them to various human diseases, technical challenges have limited their detection and accurate q...

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Detalles Bibliográficos
Autores principales: Sarin, L. Peter, Kienast, Sandra D., Leufken, Johannes, Ross, Robert L., Dziergowska, Agnieszka, Debiec, Katarzyna, Sochacka, Elzbieta, Limbach, Patrick A., Fufezan, Christian, Drexler, Hannes C.A., Leidel, Sebastian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140458/
https://www.ncbi.nlm.nih.gov/pubmed/30012570
http://dx.doi.org/10.1261/rna.065482.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140458/
https://www.ncbi.nlm.nih.gov/pubmed/30012570
http://dx.doi.org/10.1261/rna.065482.117

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