Translation elongation and mRNA stability are coupled through the ribosomal A-site

Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in eukaryotic cells. Previous work by us and others has shown that codon identity exerts a powerful influence on mRNA stability. In Saccharomyces cerevisiae, studies using a handful of reporter mRNAs show that opt...

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Detalles Bibliográficos
Autores principales: Hanson, Gavin, Alhusaini, Najwa, Morris, Nathan, Sweet, Thomas, Coller, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140462/
https://www.ncbi.nlm.nih.gov/pubmed/29997263
http://dx.doi.org/10.1261/rna.066787.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140462/
https://www.ncbi.nlm.nih.gov/pubmed/29997263
http://dx.doi.org/10.1261/rna.066787.118

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