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Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks

Histone posttranslational modifications (PTMs) regulate chromatin dynamics, DNA accessibility, and transcription to expand the genetic code. Many of these PTMs are produced through cellular metabolism to offer both feedback and feedforward regulation. Herein we describe the existence of Lys and Arg...

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Detalles Bibliográficos
Autores principales: Galligan, James J., Wepy, James A., Streeter, Matthew D., Kingsley, Philip J., Mitchener, Michelle M., Wauchope, Orrette R., Beavers, William N., Rose, Kristie L., Wang, Tina, Spiegel, David A., Marnett, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140490/
https://www.ncbi.nlm.nih.gov/pubmed/30150385
http://dx.doi.org/10.1073/pnas.1802901115