Cargando…

Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen

Candida albicans is a heterozygous diploid yeast that is a commensal of the human gastrointestinal tract and a prevalent opportunistic pathogen. Here, whole-genome sequencing was performed on multiple C. albicans isolates passaged both in vitro and in vivo to characterize the complete spectrum of mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ene, Iuliana V., Farrer, Rhys A., Hirakawa, Matthew P., Agwamba, Kennedy, Cuomo, Christina A., Bennett, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140516/
https://www.ncbi.nlm.nih.gov/pubmed/30150418
http://dx.doi.org/10.1073/pnas.1806002115