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Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen
Candida albicans is a heterozygous diploid yeast that is a commensal of the human gastrointestinal tract and a prevalent opportunistic pathogen. Here, whole-genome sequencing was performed on multiple C. albicans isolates passaged both in vitro and in vivo to characterize the complete spectrum of mu...
Autores principales: | Ene, Iuliana V., Farrer, Rhys A., Hirakawa, Matthew P., Agwamba, Kennedy, Cuomo, Christina A., Bennett, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140516/ https://www.ncbi.nlm.nih.gov/pubmed/30150418 http://dx.doi.org/10.1073/pnas.1806002115 |
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