Combination of radiation and interleukin 12 eradicates large orthotopic hepatocellular carcinoma through immunomodulation of tumor microenvironment

Immunotherapies have shown promising results in certain cancer patients. For hepatocellular carcinoma (HCC), the multiplicity of an immunotolerant microenvironment within both the tumor, and the liver per se may limit the efficacy of cancer immunotherapies. Since radiation induces immunogenic cell d...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Jen, Tsai, Yi-Ting, Lee, I-Jung, Wu, Ping-Yi, Lu, Long-Sheng, Tsao, Wen-Shan, Huang, Yi-Jou, Chang, Ching-Cheng, Ka, Shuk-Man, Tao, Mi-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140549/
https://www.ncbi.nlm.nih.gov/pubmed/30228946
http://dx.doi.org/10.1080/2162402X.2018.1477459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140549/
https://www.ncbi.nlm.nih.gov/pubmed/30228946
http://dx.doi.org/10.1080/2162402X.2018.1477459

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