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Inhibition of RON kinase potentiates anti-CTLA-4 immunotherapy to shrink breast tumors and prevent metastatic outgrowth

The advent of immune checkpoint blockade as a new strategy for immunotherapy has changed the outlook for many aggressive cancers. Although complete tumor eradication is attainable in some cases, durable clinical responses are observed only in a small fraction of patients, underlining urgent need for...

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Detalles Bibliográficos
Autores principales: Ekiz, Huseyin Atakan, Lai, Shu-Chin Alicia, Gundlapalli, Harika, Haroun, Fadi, Williams, Matthew A., Welm, Alana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140584/
https://www.ncbi.nlm.nih.gov/pubmed/30228950
http://dx.doi.org/10.1080/2162402X.2018.1480286