Duokines: a novel class of dual-acting co-stimulatory molecules acting in cis or trans

Co-stimulatory signals induced by ligands of the tumor necrosis factor superfamily (TNFSF) play a central role in T cell activation and have emerged as a promising strategy in cancer immunotherapy. Here, we established a novel class of bifunctional co-stimulatory fusion proteins with the aim to boos...

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Detalles Bibliográficos
Autores principales: Fellermeier-Kopf, Sina, Gieseke, Friederike, Sahin, Ugur, Müller, Dafne, Pfizenmaier, Klaus, Kontermann, Roland E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140609/
https://www.ncbi.nlm.nih.gov/pubmed/30228940
http://dx.doi.org/10.1080/2162402X.2018.1471442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140609/
https://www.ncbi.nlm.nih.gov/pubmed/30228940
http://dx.doi.org/10.1080/2162402X.2018.1471442

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