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Multiple Myeloma Exemplifies a Model of Cancer Based on Tissue Disruption as the Initiator Event

The standard model of multiple myeloma (MM) oncogenesis is based on the genetic instability of MM cells and presents its evolution as the emergence of clones with more and more aggressive genotypes, giving them surviving and proliferating advantage. The micro-environment has a passive role. In contr...

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Detalles Bibliográficos
Autores principales: Capp, Jean-Pascal, Bataille, Régis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140628/
https://www.ncbi.nlm.nih.gov/pubmed/30250824
http://dx.doi.org/10.3389/fonc.2018.00355